Natural variants in SARS-CoV-2 Spike protein pinpoint structural and functional hotspots with implications for prophylaxis and therapeutic strategies
Abstract In December 2019, a novel coronavirus, termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified as the cause of pneumonia with severe respiratory distress and outbreaks in Wuhan, China. The rapid and global spread of SARS-CoV-2 resulted in the coronavirus 2019 (CO...
Saved in:
Main Authors: | Suman Pokhrel, Benjamin R. Kraemer, Scott Burkholz, Daria Mochly-Rosen |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/b0aed1a133e74b9f88b53604d16bbdf5 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible 501Y.V1 and 501Y.V2 SARS-CoV-2 variants' spike protein-an in silico analysis.
by: Suman Pokhrel, et al.
Published: (2021) -
Sand spikes pinpoint powerful palaeoseismicity
by: Elmar Buchner, et al.
Published: (2021) -
Hotspot Mutations in SARS-CoV-2
by: Indrajit Saha, et al.
Published: (2021) -
Mutational Hotspot in the SARS-CoV-2 Spike Protein N-Terminal Domain Conferring Immune Escape Potential
by: Slawomir Kubik, et al.
Published: (2021) -
A third SARS-CoV-2 spike vaccination improves neutralization of variants-of-concern
by: Mitch Brinkkemper, et al.
Published: (2021)