RIF1 Links Replication Timing with Fork Reactivation and DNA Double-Strand Break Repair
Replication timing (RT) is a cellular program to coordinate initiation of DNA replication in all origins within the genome. RIF1 (replication timing regulatory factor 1) is a master regulator of RT in human cells. This role of RIF1 is associated with binding G4-quadruplexes and changes in 3D chromat...
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Auteurs principaux: | Janusz Blasiak, Joanna Szczepańska, Anna Sobczuk, Michal Fila, Elzbieta Pawlowska |
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Format: | article |
Langue: | EN |
Publié: |
MDPI AG
2021
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Accès en ligne: | https://doaj.org/article/b2a85a44d92d472fa1e093dd9c039dc1 |
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