On the heat stability of amyloid-based biological activity: insights from thermal degradation of insulin fibrils.
Formation of amyloid fibrils in vivo has been linked to disorders such as Alzheimer's disease and prion-associated transmissible spongiform encephalopathies. One of the characteristic features of amyloid fibrils is the high thermodynamic stability relative both to native and disordered states w...
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Main Authors: | , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Subjects: | |
Online Access: | https://doaj.org/article/b31ee8b3fde1447ebeefd06a43bea34e |
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