Intermolecular steric inhibition of Ephexin4 is relieved by Elmo1

Abstract Ephexin4, a guanine nucleotide-exchange factor for RhoG, promotes engulfment of apoptotic cells and cancer cell migration in a RhoG-dependent manner, which is synergistically augmented by Elmo1, an Ephexin4-interacting protein. However, the underlying molecular mechanism remains elusive. He...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kwanhyeong Kim, Juyeon Lee, Sang-Ah Lee, Hyunji Moon, Boyeon Park, Deokhwan Kim, Young-Eun Joo, Daeho Park
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/b45c903de0bc48c98bb1fcbc24f70091
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!