Triosephosphate Isomerase Is Dispensable <italic toggle="yes">In Vitro</italic> yet Essential for <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> To Establish Infection

Triosephosphate Isomerase Is Dispensable <italic toggle="yes">In Vitro</italic> yet Essential for <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> To Establish Infection

ABSTRACT Triosephosphate isomerase (TPI) catalyzes the interconversion of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (G3P). This reaction is required for glycolysis and gluconeogenesis, and tpi has been predicted to be essential for growth of Mycobacterium tuberculosis. However...

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Bibliographic Details
Main Authors: Carolina Trujillo, Antje Blumenthal, Joeli Marrero, Kyu Y. Rhee, Dirk Schnappinger, Sabine Ehrt
Format: article
Language:EN
Published: American Society for Microbiology 2014
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/b45e48d5861d431993d2aea75d2cc850
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