Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data.

Broadly neutralizing monoclonal antibodies effective against the majority of circulating isolates of HIV-1 have been isolated from a small number of infected individuals. Definition of the conformational epitopes on the HIV spike to which these antibodies bind is of great value in defining targets f...

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Autores principales: Andrew L Ferguson, Emilia Falkowska, Laura M Walker, Michael S Seaman, Dennis R Burton, Arup K Chakraborty
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/b75e57862cb246188f63415256146f2e
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