Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data.

por Andrew L Ferguson, Emilia Falkowska, Laura M Walker, Michael S Seaman, Dennis R Burton, Arup K Chakraborty
Publicado 2013

Adenovirus prime, Env protein boost vaccine protects against neutralization-resistant SIVsmE660 variants in rhesus monkeys

por Brandon F. Keele, Wenjun Li, Erica N. Borducchi, Joseph P. Nkolola, Peter Abbink, Bing Chen, Michael S. Seaman, Dan H. Barouch
Publicado 2017

Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein

por Alessandro Piai, Qingshan Fu, Yongfei Cai, Fadi Ghantous, Tianshu Xiao, Md Munan Shaik, Hanqin Peng, Sophia Rits-Volloch, Wen Chen, Michael S. Seaman, Bing Chen, James J. Chou
Publicado 2020

Durable protection against repeated penile exposures to simian-human immunodeficiency virus by broadly neutralizing antibodies

por David A. Garber, Debra R. Adams, Patricia Guenthner, James Mitchell, Kristen Kelley, Till Schoofs, Anna Gazumyan, Martha Nason, Michael S. Seaman, Janet McNicholl, Michel C. Nussenzweig, Walid Heneine
Publicado 2020

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice

por Andrew T. McGuire, Matthew D. Gray, Pia Dosenovic, Alexander D. Gitlin, Natalia T. Freund, John Petersen, Colin Correnti, William Johnsen, Robert Kegel, Andrew B. Stuart, Jolene Glenn, Michael S. Seaman, William R. Schief, Roland K. Strong, Michel C. Nussenzweig, Leonidas Stamatatos
Publicado 2016

Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations

por Qifeng Han, Julia A. Jones, Nathan I. Nicely, Rachel K. Reed, Xiaoying Shen, Katayoun Mansouri, Mark Louder, Ashley M. Trama, S. Munir Alam, Robert J. Edwards, Mattia Bonsignori, Georgia D. Tomaras, Bette Korber, David C. Montefiori, John R. Mascola, Michael S. Seaman, Barton F. Haynes, Kevin O. Saunders
Publicado 2019

The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.

por Devin Sok, Uri Laserson, Jonathan Laserson, Yi Liu, Francois Vigneault, Jean-Philippe Julien, Bryan Briney, Alejandra Ramos, Karen F Saye, Khoa Le, Alison Mahan, Shenshen Wang, Mehran Kardar, Gur Yaari, Laura M Walker, Birgitte B Simen, Elizabeth P St John, Po-Ying Chan-Hui, Kristine Swiderek, Steven H Kleinstein, Galit Alter, Michael S Seaman, Arup K Chakraborty, Daphne Koller, Ian A Wilson, George M Church, Dennis R Burton, Pascal Poignard
Publicado 2013