Maintenance and loss of endocytic organelle integrity: mechanisms and implications for antigen cross-presentation
The membranes of endosomes, phagosomes and macropinosomes can become damaged by the physical properties of internalized cargo, by active pathogenic invasion or by cellular processes, including endocytic maturation. Loss of membrane integrity is often deleterious and is, therefore, prevented by mitig...
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Main Authors: | Eleanor Childs, Conor M. Henry, Johnathan Canton, Caetano Reis e Sousa |
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Format: | article |
Language: | EN |
Published: |
The Royal Society
2021
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Subjects: | |
Online Access: | https://doaj.org/article/b8b323d935d047ccba6ca37209913795 |
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