Nano-hydroxyapatite accelerates vascular calcification via lysosome impairment and autophagy dysfunction in smooth muscle cells

Vascular calcification (VC) is a common characteristic of aging, diabetes, chronic renal failure, and atherosclerosis. The basic component of VC is hydroxyapatite (HAp). Nano-sized HAp (nHAp) has been identified to play an essential role in the development of pathological calcification of vasculatur...

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Main Authors: Qi Liu, Yi Luo, Yun Zhao, Pingping Xiang, Jinyun Zhu, Wangwei Jing, Wenjing Jin, Mingyao Chen, Ruikang Tang, Hong Yu
Format: article
Language:EN
Published: KeAi Communications Co., Ltd. 2022
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Online Access:https://doaj.org/article/b96630a5c0ae41f7af9cee6b1831fc55
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