Mycobacterium tuberculosis WhiB3 maintains redox homeostasis by regulating virulence lipid anabolism to modulate macrophage response.

The metabolic events associated with maintaining redox homeostasis in Mycobacterium tuberculosis (Mtb) during infection are poorly understood. Here, we discovered a novel redox switching mechanism by which Mtb WhiB3 under defined oxidizing and reducing conditions differentially modulates the assimil...

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Autores principales: Amit Singh, David K Crossman, Deborah Mai, Loni Guidry, Martin I Voskuil, Matthew B Renfrow, Adrie J C Steyn
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/bd5a30f329df4ff6bfce98bb7332f434
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