Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome

Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome

ABSTRACT Obstructive sleep apnea (OSA) is a common disorder characterized by episodic obstruction to breathing due to upper airway collapse during sleep. Because of the episodic airway obstruction, intermittently low O2 (hypoxia) and high CO2 (hypercapnia) ensue. OSA has been associated with adverse...

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Bibliographic Details
Main Authors: Anupriya Tripathi, Alexey V. Melnik, Jin Xue, Orit Poulsen, Michael J. Meehan, Gregory Humphrey, Lingjing Jiang, Gail Ackermann, Daniel McDonald, Dan Zhou, Rob Knight, Pieter C. Dorrestein, Gabriel G. Haddad
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
cardiovascular
metabolism
microbiome
sleep apnea
Microbiology
QR1-502
Online Access:https://doaj.org/article/c01326f5b4b0417ba6d9d3532c83605c
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https://doaj.org/article/c01326f5b4b0417ba6d9d3532c83605c

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