Programming mRNA decay to modulate synthetic circuit resource allocation

Synthetic circuits in host cells compete with endogenous processes for limited resources. Here the authors use MazF to funnel cellular resources to a synthetic circuit to increase product production and demonstrate how resource allocation can be manipulated.

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Auteurs principaux: Ophelia S. Venturelli, Mika Tei, Stefan Bauer, Leanne Jade G. Chan, Christopher J. Petzold, Adam P Arkin
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/c43786f35a0d4d08ac93c75c2b65d83c
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