Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases

Terpene cyclases catalyze the formation of diverse hydrocarbon scaffolds found in terpenoids. Here, the authors report the cryptic function of class I terpene cyclases as aromatic prenyltransferases and the universality of this cryptic feature is confirmed using enzymes from different sources.

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Autores principales: Haibing He, Guangkai Bian, Corey J. Herbst-Gervasoni, Takahiro Mori, Stephen A. Shinsky, Anwei Hou, Xin Mu, Minjian Huang, Shu Cheng, Zixin Deng, David W. Christianson, Ikuro Abe, Tiangang Liu
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c70d380b1bf6424697e7827e67324201
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spelling oai:doaj.org-article:c70d380b1bf6424697e7827e673242012021-12-02T14:53:37ZDiscovery of the cryptic function of terpene cyclases as aromatic prenyltransferases10.1038/s41467-020-17642-22041-1723https://doaj.org/article/c70d380b1bf6424697e7827e673242012020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17642-2https://doaj.org/toc/2041-1723Terpene cyclases catalyze the formation of diverse hydrocarbon scaffolds found in terpenoids. Here, the authors report the cryptic function of class I terpene cyclases as aromatic prenyltransferases and the universality of this cryptic feature is confirmed using enzymes from different sources.Haibing HeGuangkai BianCorey J. Herbst-GervasoniTakahiro MoriStephen A. ShinskyAnwei HouXin MuMinjian HuangShu ChengZixin DengDavid W. ChristiansonIkuro AbeTiangang LiuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Haibing He
Guangkai Bian
Corey J. Herbst-Gervasoni
Takahiro Mori
Stephen A. Shinsky
Anwei Hou
Xin Mu
Minjian Huang
Shu Cheng
Zixin Deng
David W. Christianson
Ikuro Abe
Tiangang Liu
Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases
description Terpene cyclases catalyze the formation of diverse hydrocarbon scaffolds found in terpenoids. Here, the authors report the cryptic function of class I terpene cyclases as aromatic prenyltransferases and the universality of this cryptic feature is confirmed using enzymes from different sources.
format article
author Haibing He
Guangkai Bian
Corey J. Herbst-Gervasoni
Takahiro Mori
Stephen A. Shinsky
Anwei Hou
Xin Mu
Minjian Huang
Shu Cheng
Zixin Deng
David W. Christianson
Ikuro Abe
Tiangang Liu
author_facet Haibing He
Guangkai Bian
Corey J. Herbst-Gervasoni
Takahiro Mori
Stephen A. Shinsky
Anwei Hou
Xin Mu
Minjian Huang
Shu Cheng
Zixin Deng
David W. Christianson
Ikuro Abe
Tiangang Liu
author_sort Haibing He
title Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases
title_short Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases
title_full Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases
title_fullStr Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases
title_full_unstemmed Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases
title_sort discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c70d380b1bf6424697e7827e67324201
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