A genetic cell context-dependent role for ZEB1 in lung cancer

ZEB1 is a driver of epithelial-to-mesenchymal transition that usually promotes lung cancer in the context of KRAS mutation. Here, the authors uncover a growth suppressive role for ZEB1 in EGFRmutant lung adenocarcinoma, thus elucidating the context dependent function of this protein.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ting Zhang, Lixia Guo, Chad J. Creighton, Qiang Lu, Don L. Gibbons, Eunhee S. Yi, Bo Deng, Julian R. Molina, Zhifu Sun, Ping Yang, Yanan Yang
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
Q
Accès en ligne:https://doaj.org/article/c8af796cf1bc4dac90587bd1750bc508
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!