A genetic cell context-dependent role for ZEB1 in lung cancer

A genetic cell context-dependent role for ZEB1 in lung cancer

ZEB1 is a driver of epithelial-to-mesenchymal transition that usually promotes lung cancer in the context of KRAS mutation. Here, the authors uncover a growth suppressive role for ZEB1 in EGFRmutant lung adenocarcinoma, thus elucidating the context dependent function of this protein.

Guardado en:
Detalles Bibliográficos
Autores principales: Ting Zhang, Lixia Guo, Chad J. Creighton, Qiang Lu, Don L. Gibbons, Eunhee S. Yi, Bo Deng, Julian R. Molina, Zhifu Sun, Ping Yang, Yanan Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/c8af796cf1bc4dac90587bd1750bc508
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares