The N-terminal tail of hERG contains an amphipathic α-helix that regulates channel deactivation.
The cytoplasmic N-terminal domain of the human ether-a-go-go related gene (hERG) K+ channel is critical for the slow deactivation kinetics of the channel. However, the mechanism(s) by which the N-terminal domain regulates deactivation remains to be determined. Here we show that the solution NMR stru...
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Main Authors: | , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
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Subjects: | |
Online Access: | https://doaj.org/article/cd58b092df8e48f98ebad7ea3a2f7210 |
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