A broad analysis of resistance development in the malaria parasite
It is unclear whether new antimalarial compounds may rapidly lose effectiveness in the field because of parasite resistance. Here, Corey et al.investigate the acquisition of drug resistance and the extent to which common resistance mechanisms decrease susceptibility to a diverse set of 50 antimalari...
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Nature Portfolio
2016
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oai:doaj.org-article:ce1be14e28304ebdb5d80a44a4d4e3b42021-12-02T14:38:53ZA broad analysis of resistance development in the malaria parasite10.1038/ncomms119012041-1723https://doaj.org/article/ce1be14e28304ebdb5d80a44a4d4e3b42016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11901https://doaj.org/toc/2041-1723It is unclear whether new antimalarial compounds may rapidly lose effectiveness in the field because of parasite resistance. Here, Corey et al.investigate the acquisition of drug resistance and the extent to which common resistance mechanisms decrease susceptibility to a diverse set of 50 antimalarial compounds.Victoria C. CoreyAmanda K. LukensEva S. IstvanMarcus C. S. LeeVirginia FrancoPamela MagistradoOlivia Coburn-FlynnTomoyo Sakata-KatoOlivia FuchsNina F. GnädigGreg GoldgofMaria LinaresMaria G. Gomez-LorenzoCristina De CózarMaria Jose Lafuente-MonasterioSara PratsStephan MeisterOlga TanaseichukMelanie WreeYingyao ZhouPaul A. WillisFrancisco-Javier GamoDaniel E. GoldbergDavid A. FidockDyann F. WirthElizabeth A. WinzelerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Victoria C. Corey Amanda K. Lukens Eva S. Istvan Marcus C. S. Lee Virginia Franco Pamela Magistrado Olivia Coburn-Flynn Tomoyo Sakata-Kato Olivia Fuchs Nina F. Gnädig Greg Goldgof Maria Linares Maria G. Gomez-Lorenzo Cristina De Cózar Maria Jose Lafuente-Monasterio Sara Prats Stephan Meister Olga Tanaseichuk Melanie Wree Yingyao Zhou Paul A. Willis Francisco-Javier Gamo Daniel E. Goldberg David A. Fidock Dyann F. Wirth Elizabeth A. Winzeler A broad analysis of resistance development in the malaria parasite |
| description |
It is unclear whether new antimalarial compounds may rapidly lose effectiveness in the field because of parasite resistance. Here, Corey et al.investigate the acquisition of drug resistance and the extent to which common resistance mechanisms decrease susceptibility to a diverse set of 50 antimalarial compounds. |
| format |
article |
| author |
Victoria C. Corey Amanda K. Lukens Eva S. Istvan Marcus C. S. Lee Virginia Franco Pamela Magistrado Olivia Coburn-Flynn Tomoyo Sakata-Kato Olivia Fuchs Nina F. Gnädig Greg Goldgof Maria Linares Maria G. Gomez-Lorenzo Cristina De Cózar Maria Jose Lafuente-Monasterio Sara Prats Stephan Meister Olga Tanaseichuk Melanie Wree Yingyao Zhou Paul A. Willis Francisco-Javier Gamo Daniel E. Goldberg David A. Fidock Dyann F. Wirth Elizabeth A. Winzeler |
| author_facet |
Victoria C. Corey Amanda K. Lukens Eva S. Istvan Marcus C. S. Lee Virginia Franco Pamela Magistrado Olivia Coburn-Flynn Tomoyo Sakata-Kato Olivia Fuchs Nina F. Gnädig Greg Goldgof Maria Linares Maria G. Gomez-Lorenzo Cristina De Cózar Maria Jose Lafuente-Monasterio Sara Prats Stephan Meister Olga Tanaseichuk Melanie Wree Yingyao Zhou Paul A. Willis Francisco-Javier Gamo Daniel E. Goldberg David A. Fidock Dyann F. Wirth Elizabeth A. Winzeler |
| author_sort |
Victoria C. Corey |
| title |
A broad analysis of resistance development in the malaria parasite |
| title_short |
A broad analysis of resistance development in the malaria parasite |
| title_full |
A broad analysis of resistance development in the malaria parasite |
| title_fullStr |
A broad analysis of resistance development in the malaria parasite |
| title_full_unstemmed |
A broad analysis of resistance development in the malaria parasite |
| title_sort |
broad analysis of resistance development in the malaria parasite |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/ce1be14e28304ebdb5d80a44a4d4e3b4 |
| work_keys_str_mv |
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