A Mutation Upstream of the <italic toggle="yes">rplN-rpsD</italic> Ribosomal Operon Downregulates <named-content content-type="genus-species">Bordetella pertussis</named-content> Virulence Factor Production without Compromising Bacterial Survival within Human Macrophages
ABSTRACT The BvgS/BvgA two-component system controls expression of ∼550 genes of Bordetella pertussis, of which, ∼245 virulence-related genes are positively regulated by the BvgS-phosphorylated transcriptional regulator protein BvgA (BvgA∼P). We found that a single G-to-T nucleotide transversion in...
Guardado en:
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2020
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/cf6ec5a1115a47508d4d8820cec5b491 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|