Exosome-delivered EGFR regulates liver microenvironment to promote gastric cancer liver metastasis
EGFR signalling has been linked to cancer development but whether it has any role in pre-metastatic niche formation is not known. Here the authors show that gastric cancer cells send EGFR through exosomes to the liver where it causes the establishment of a favourable microenvironment thus promoting...
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Main Authors: | , , , , , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Subjects: | |
Online Access: | https://doaj.org/article/d4d3d21a7c36464a8fb02e163d543374 |
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