Knockout of the KH-Type Splicing Regulatory Protein Drives Glomerulonephritis in MRL-Fas<sup>lpr</sup> Mice
KH-type splicing regulatory protein (KSRP) is an RNA-binding protein that promotes mRNA decay and thereby negatively regulates cytokine expression at the post-transcriptional level. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by dysregulated cytokine expression causing...
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Main Authors: | Lisa Schmidtke, Myriam Meineck, Sabrina Saurin, Svenja Otten, Fabian Gather, Katharina Schrick, Rudolf Käfer, Wilfried Roth, Hartmut Kleinert, Julia Weinmann-Menke, Andrea Pautz |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Subjects: | |
Online Access: | https://doaj.org/article/da5060350d0742d68f0b00959c48e6d9 |
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