Rational extension of the ribosome biogenesis pathway using network-guided genetics.
Biogenesis of ribosomes is an essential cellular process conserved across all eukaryotes and is known to require >170 genes for the assembly, modification, and trafficking of ribosome components through multiple cellular compartments. Despite intensive study, this pathway likely involves many add...
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Main Authors: | Zhihua Li, Insuk Lee, Emily Moradi, Nai-Jung Hung, Arlen W Johnson, Edward M Marcotte |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2009
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Online Access: | https://doaj.org/article/dba530d8aa634d3295d41a9626dbda62 |
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