Genetic variation of the IL-28B promoter affecting gene expression.
The current standard of care for the treatment of chronic hepatitis C is pegylated interferon-α (PEG-IFNα) and ribavirin (RBV). The treatment achieves a sustained viral clearance in only approximately 50% of patients. Recent whole genome association studies revealed that single nucleotide polymorphi...
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Main Authors: | Masaya Sugiyama, Yasuhito Tanaka, Takaji Wakita, Makoto Nakanishi, Masashi Mizokami |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2011
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Online Access: | https://doaj.org/article/e43f1a44991d43adadedf67633e8c03a |
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