Neonatal administration of a subanaesthetic dose of JM-1232(−) in mice results in no behavioural deficits in adulthood
Abstract In animal models, neonatal exposure of general anaesthetics significantly increases apoptosis in the brain, resulting in persistent behavioural deficits later in adulthood. Consequently, there is growing concern about the use of general anaesthetics in obstetric and paediatric practice. JM-...
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Main Authors: | Koji Iwanaga, Yasushi Satoh, Ryosuke Akai, Toshiaki Ishizuka, Tomiei Kazama, Takehiko Ikeda |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/e6af7627e5cb46d1be1b4146f12f9228 |
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