Binding Heterogeneity of <named-content content-type="genus-species">Plasmodium falciparum</named-content> to Engineered 3D Brain Microvessels Is Mediated by EPCR and ICAM-1
ABSTRACT Cerebral malaria is a severe neurological complication associated with sequestration of Plasmodium falciparum-infected erythrocytes (IE) in the brain microvasculature, but the specific binding interactions remain under debate. Here, we have generated an engineered three-dimensional (3D) hum...
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Main Authors: | , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2019
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Subjects: | |
Online Access: | https://doaj.org/article/e8baabff64bb490f8a669a8d2a19155f |
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