Transcriptomic Changes Highly Similar to Alzheimer’s Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging

Aging is a major risk factor for late-onset Alzheimer’s disease (LOAD). How aging contributes to the development of LOAD remains elusive. In this study, we examined multiple large-scale transcriptomic datasets from both normal aging and LOAD brains to understand the molecular interconnection between...

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Autores principales: Shouneng Peng, Lu Zeng, Jean-Vianney Haure-Mirande, Minghui Wang, Derek M. Huffman, Vahram Haroutunian, Michelle E. Ehrlich, Bin Zhang, Zhidong Tu
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/edd42ca4f7c84ac29d263d4073145dca
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