Predicted Epitope Abundance Supports Vaccine-Induced Cytotoxic Protection Against SARS-CoV-2 Variants of Concern

The effect of emerging SARS-CoV-2 variants on vaccine efficacy is of critical importance. In this study, the potential impact of mutations that facilitate escape from the cytotoxic cellular immune response in these new virus variants for the 551 most abundant HLA class I alleles was analyzed. Comput...

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Auteurs principaux: Antonio J. Martín-Galiano, Francisco Díez-Fuertes, Michael J. McConnell, Daniel López
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
Sujets:
HLA
Accès en ligne:https://doaj.org/article/ef97a7e4b38a45e0b1cc6dfde71859aa
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