SIRT1 Promotes M2 Microglia Polarization via Reducing ROS-Mediated NLRP3 Inflammasome Signaling After Subarachnoid Hemorrhage
Mounting evidence has suggested that modulating microglia polarization from pro-inflammatory M1 phenotype to anti-inflammatory M2 state might be a potential therapeutic approach in the treatment of subarachnoid hemorrhage (SAH) injury. Our previous study has indicated that sirtuin 1 (SIRT1) could am...
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Main Authors: | , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
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Subjects: | |
Online Access: | https://doaj.org/article/efa1ff860b80456184819e75f052903e |
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