Shining a light on dark sequencing: characterising errors in Ion Torrent PGM data.

The Ion Torrent Personal Genome Machine (PGM) is a new sequencing platform that substantially differs from other sequencing technologies by measuring pH rather than light to detect polymerisation events. Using re-sequencing datasets, we comprehensively characterise the biases and errors introduced b...

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Bibliographic Details
Main Authors: Lauren M Bragg, Glenn Stone, Margaret K Butler, Philip Hugenholtz, Gene W Tyson
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/f0994714caee437dbf8ddc02c901ac70
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