Shining a light on dark sequencing: characterising errors in Ion Torrent PGM data.
The Ion Torrent Personal Genome Machine (PGM) is a new sequencing platform that substantially differs from other sequencing technologies by measuring pH rather than light to detect polymerisation events. Using re-sequencing datasets, we comprehensively characterise the biases and errors introduced b...
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Autores principales: | Lauren M Bragg, Glenn Stone, Margaret K Butler, Philip Hugenholtz, Gene W Tyson |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/f0994714caee437dbf8ddc02c901ac70 |
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