Functional rotation of the transporter AcrB: insights into drug extrusion from simulations.
The tripartite complex AcrAB-TolC is the major efflux system in Escherichia coli. It extrudes a wide spectrum of noxious compounds out of the bacterium, including many antibiotics. Its active part, the homotrimeric transporter AcrB, is responsible for the selective binding of substrates and energy t...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2010
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/f09fe10093e74a379063b2e3610e2371 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|