Abnormal mitochondrial L-arginine transport contributes to the pathogenesis of heart failure and rexoygenation injury.

<h4>Background</h4>Impaired mitochondrial function is fundamental feature of heart failure (HF) and myocardial ischemia. In addition to the effects of heightened oxidative stress, altered nitric oxide (NO) metabolism, generated by a mitochondrial NO synthase, has also been proposed to im...

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Bibliographic Details
Main Authors: David Williams, Kylie M Venardos, Melissa Byrne, Mandar Joshi, Duncan Horlock, Nicholas T Lam, Paul Gregorevic, Sean L McGee, David M Kaye
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
R
Q
Online Access:https://doaj.org/article/f11909e9fbd049feb59ddde30b0a8a64
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