A novel ex vivo isolation and expansion procedure for chimeric antigen receptor engrafted human T cells.
Genetically engineered T lymphocytes are a promising option for cancer therapy. Prior to adoptive transfer they have to be expanded in vitro to reach therapeutically sufficient numbers. So far, no universal method exists for selective in vitro expansion of engineered T lymphocytes. In order to overc...
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Auteurs principaux: | , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2014
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Accès en ligne: | https://doaj.org/article/f142152a744f4caf9d7376f363460801 |
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