Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins

Protein repeats may be considered a paradox, being evolutionarily conserved yet also hotspots of protein evolution associated with innovation. Here, the authors use a novel method to show that new repeats undergo rapid divergence within species, but are then fixed and conserved between species.

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Detalles Bibliográficos
Autores principales:	Erez Persi, Yuri I. Wolf, Eugene V Koonin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f21094ba5e1f44e5a9b02459431657e9
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spelling	oai:doaj.org-article:f21094ba5e1f44e5a9b02459431657e92021-12-02T17:31:20ZPositive and strongly relaxed purifying selection drive the evolution of repeats in proteins10.1038/ncomms135702041-1723https://doaj.org/article/f21094ba5e1f44e5a9b02459431657e92016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13570https://doaj.org/toc/2041-1723Protein repeats may be considered a paradox, being evolutionarily conserved yet also hotspots of protein evolution associated with innovation. Here, the authors use a novel method to show that new repeats undergo rapid divergence within species, but are then fixed and conserved between species.Erez PersiYuri I. WolfEugene V KooninNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erez Persi Yuri I. Wolf Eugene V Koonin Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins
description	Protein repeats may be considered a paradox, being evolutionarily conserved yet also hotspots of protein evolution associated with innovation. Here, the authors use a novel method to show that new repeats undergo rapid divergence within species, but are then fixed and conserved between species.
format	article
author	Erez Persi Yuri I. Wolf Eugene V Koonin
author_facet	Erez Persi Yuri I. Wolf Eugene V Koonin
author_sort	Erez Persi
title	Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins
title_short	Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins
title_full	Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins
title_fullStr	Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins
title_full_unstemmed	Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins
title_sort	positive and strongly relaxed purifying selection drive the evolution of repeats in proteins
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f21094ba5e1f44e5a9b02459431657e9
work_keys_str_mv	AT erezpersi positiveandstronglyrelaxedpurifyingselectiondrivetheevolutionofrepeatsinproteins AT yuriiwolf positiveandstronglyrelaxedpurifyingselectiondrivetheevolutionofrepeatsinproteins AT eugenevkoonin positiveandstronglyrelaxedpurifyingselectiondrivetheevolutionofrepeatsinproteins
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Positive and strongly relaxed purifying selection drive the evolution of repeats in proteins

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