A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells.

<h4>Background</h4>Polyploidy is a prominent feature of many human cancers, and it has long been hypothesized that polyploidy may contribute to tumorigenesis by promoting genomic instability. In this study, we investigated whether polyploidy per se induced by a relevant oncogene can prom...

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Bibliographic Details
Main Authors: Meejeon Roh, Omar E Franco, Simon W Hayward, Riet van der Meer, Sarki A Abdulkadir
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2008
Subjects:
R
Q
Online Access:https://doaj.org/article/f7c3d302cc6643d9942ab3d9f8a02b8d
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