HLA-B and cysteinylated ligands distinguish the antigen presentation landscape of extracellular vesicles
Bauzá-Martinez et al. analyzed the HLA-I peptide ligandome in extracellular vesicles (EVs) from an EBV-immortalized B cell line, JY, and compare HLA-I-binding peptides recovered from EVs to those recovered from whole-cells. The authors report an enrichment for HLA-B-binding peptides and for post-tra...
Saved in:
Main Authors: | Julia Bauzá-Martinez, Albert J. R. Heck, Wei Wu |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/fbaffa91552645889971ca88dba9c128 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The HLA Ligandome Comprises a Limited Repertoire of O-GlcNAcylated Antigens Preferentially Associated With HLA-B*07:02
by: Soumya Mukherjee, et al.
Published: (2021) -
HLA-G/sHLA-G and HLA-G-Bearing Extracellular Vesicles in Cancers: Potential Role as Biomarkers
by: Peilong Li, et al.
Published: (2021) -
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors
by: Anastasiia Gusach, et al.
Published: (2019) -
Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cells.
by: Ladan Parhamifar, et al.
Published: (2010) -
Diagnostic and Prognostic Utility of the Extracellular Vesicles Subpopulations Present in Pleural Effusion
by: Joman Javadi, et al.
Published: (2021)