Polimorfismo +49 A/G del gen del antígeno 4 del linfocito T citotóxico (CTLA-4) en la diabetes tipo 1: Asociación con el perfil de anticuerpos y citoquinas

Background: Cytotoxic T lymphocyte associated antigen 4 (CTLA-4) has been one ofthe non HLA genes more commonly studied in type 1 diabetes mellitus (TID). CTLA-4 is a co-stimulation protein that has a key role in the negative regulation ofT cells and is related with a functional cytokine imbalance,...

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Main Authors: Pérez B,Francisco, Codner D,Ethel, Ángel B,Bárbara, Balic N,Iván, Carrasco P,Elena
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2009
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Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000300001
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