Polimorfismo +49 A/G del gen del antígeno 4 del linfocito T citotóxico (CTLA-4) en la diabetes tipo 1: Asociación con el perfil de anticuerpos y citoquinas
Background: Cytotoxic T lymphocyte associated antigen 4 (CTLA-4) has been one ofthe non HLA genes more commonly studied in type 1 diabetes mellitus (TID). CTLA-4 is a co-stimulation protein that has a key role in the negative regulation ofT cells and is related with a functional cytokine imbalance,...
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| Auteurs principaux: | , , , , |
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| Langue: | Spanish / Castilian |
| Publié: |
Sociedad Médica de Santiago
2009
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| Accès en ligne: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000300001 |
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