Engraftment of human induced pluripotent stem cell-derived myogenic progenitors restores dystrophin in mice with duchenne muscular dystrophy

Engraftment of human induced pluripotent stem cell-derived myogenic progenitors restores dystrophin in mice with duchenne muscular dystrophy

Abstract Background: Duchenne muscular dystrophy (DMD) is a devastating genetic muscular disorder with no effective treatment that is caused by the loss of dystrophin. Human induced pluripotent stem cells (hiPSCs) offer a promising unlimited resource for cell-based therapies of muscular dystrophy....

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Autores principales: He,Ruojie, Li,Huan, Wang,Liang, Li,Yaqin, Zhang,Yu, Chen,Menglong, Zhu,Yuling, Zhang,Cheng
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2020
Materias:
Duchenne muscular dystrophy
Human induced pluripotent stem cells
Myogenic progenitors
Muscle regeneration
Satellite cells
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602020000100218
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