The Breadth and Molecular Basis of Hcp-Driven Type VI Secretion System Effector Delivery

por Sophie A. Howard, R. Christopher D. Furniss, Dora Bonini, Himani Amin, Patricia Paracuellos, David Zlotkin, Tiago R. D. Costa, Asaf Levy, Despoina A. I. Mavridou, Alain Filloux
Publicado 2021

The Cyclin Cln1 Controls Polyploid Titan Cell Formation following a Stress-Induced G ₂ Arrest in Cryptococcus

por Sophie Altamirano, Zhongming Li, Man Shun Fu, Minna Ding, Sophie R. Fulton, J. Marina Yoder, Vy Tran, Kirsten Nielsen
Publicado 2021

GP96 Drives Exacerbation of Secondary Bacterial Pneumonia following Influenza A Virus Infection

por Tomoko Sumitomo, Masanobu Nakata, Satoshi Nagase, Yuki Takahara, Mariko Honda-Ogawa, Yasushi Mori, Yukako Akamatsu, Masaya Yamaguchi, Shigefumi Okamoto, Shigetada Kawabata
Publicado 2021

<i>In Vitro</i> Viral Evolution Identifies a Critical Residue in the Alphaherpesvirus Fusion Glycoprotein B Ectodomain That Controls gH/gL-Independent Entry

por Melina Vallbracht, Henriette Lötzsch, Barbara G. Klupp, Walter Fuchs, Benjamin Vollmer, Kay Grünewald, Marija Backovic, Felix A. Rey, Thomas C. Mettenleiter
Publicado 2021

Genome Scale Analysis Reveals IscR Directly and Indirectly Regulates Virulence Factor Genes in Pathogenic <i>Yersinia</i>

por David Balderas, Erin Mettert, Hanh N. Lam, Rajdeep Banerjee, Tomas Gverzdys, Pablo Alvarez, Geetha Saarunya, Natasha Tanner, Adam Zoubedi, Yahan Wei, Patricia J. Kiley, Victoria Auerbuch
Publicado 2021

Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[ <i>a</i> ]Pyrene Metabolite Profile and Its Distribution in 3D Skin

por Lisa Lemoine, Dilan Bayrambey, Alexander Roloff, Christoph Hutzler, Andreas Luch, Tewes Tralau
Publicado 2021

Copper Resistance Promotes Fitness of Methicillin-Resistant Staphylococcus aureus during Urinary Tract Infection

por Panatda Saenkham-Huntsinger, Amanda N. Hyre, Braden S. Hanson, George L. Donati, L. Garry Adams, Chanelle Ryan, Alejandra Londoño, Ahmed M. Moustafa, Paul J. Planet, Sargurunathan Subashchandrabose
Publicado 2021

A Bacterial Inflammation Sensor Regulates c-di-GMP Signaling, Adhesion, and Biofilm Formation

por Arden Perkins, Dan A. Tudorica, Raphael D. Teixeira, Tilman Schirmer, Lindsay Zumwalt, O. Maduka Ogba, C. Keith Cassidy, Phillip J. Stansfeld, Karen Guillemin
Publicado 2021

Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate

por Kimberly K. Kajihara, Homer Pantua, Hilda Hernandez-Barry, Meredith Hazen, Kiran Deshmukh, Nancy Chiang, Rachana Ohri, Erick R. Castellanos, Lynn Martin, Marissa L. Matsumoto, Jian Payandeh, Kelly M. Storek, Kellen Schneider, Peter A. Smith, Michael F. T. Koehler, Siao Ping Tsai, Richard Vandlen, Kelly M. Loyet, Gerald Nakamura, Thomas Pillow, Dhaya Seshasayee, Sharookh B. Kapadia, Wouter L. W. Hazenbos
Publicado 2021

Cellular Calcium Levels Influenced by NCA-2 Impact Circadian Period Determination in <i>Neurospora</i>

por Bin Wang, Xiaoying Zhou, Scott A. Gerber, Jennifer J. Loros, Jay C. Dunlap
Publicado 2021

Subversion of Lipopolysaccharide Signaling in Gingival Keratinocytes via MCPIP-1 Degradation as a Novel Pathogenic Strategy of Inflammophilic Pathobionts

por Anna Gasiorek, Ewelina Dobosz, Barbara Potempa, Izabela Ciaston, Mateusz Wilamowski, Zuzanna Oruba, Richard J. Lamont, Jolanta Jura, Jan Potempa, Joanna Koziel
Publicado 2021

Longitudinal Multi-omics and Microbiome Meta-analysis Identify an Asymptomatic Gingival State That Links Gingivitis, Periodontitis, and Aging

por Shi Huang, Tao He, Feng Yue, Xiujun Xu, Lijiang Wang, Pengfei Zhu, Fei Teng, Zheng Sun, Xiaohui Liu, Gongchao Jing, Xiaoquan Su, Lijian Jin, Jiquan Liu, Jian Xu
Publicado 2021

A Cyanobacterial Component Required for Pilus Biogenesis Affects the Exoproteome

por Yevgeni Yegorov, Eleonora Sendersky, Shaul Zilberman, Elad Nagar, Hiba Waldman Ben-Asher, Eyal Shimoni, Ryan Simkovsky, Susan S. Golden, Andy LiWang, Rakefet Schwarz
Publicado 2021

Functional Anatomy of the Trimer Apex Reveals Key Hydrophobic Constraints That Maintain the HIV-1 Envelope Spike in a Closed State

por Peng Zhang, Alice L. Kwon, Christina Guzzo, Qingbo Liu, Hana Schmeisser, Huiyi Miao, Yin Lin, Raffaello Cimbro, Jinghe Huang, Mark Connors, Stephen D. Schmidt, Michael A. Dolan, Anthony A. Armstrong, Paolo Lusso
Publicado 2021

FRQ-CK1 Interaction Underlies Temperature Compensation of the <i>Neurospora</i> Circadian Clock

por Yue Hu, Xiaolan Liu, Qiaojia Lu, Yulin Yang, Qun He, Yi Liu, Xiao Liu
Publicado 2021

Colicin-Mediated Transport of DNA through the Iron Transporter FepA

por Ruth Cohen-Khait, Ameya Harmalkar, Phuong Pham, Melissa N. Webby, Nicholas G. Housden, Emma Elliston, Jonathan T. S. Hopper, Shabaz Mohammed, Carol V. Robinson, Jeffrey J. Gray, Colin Kleanthous
Publicado 2021

Neutralization of SARS-CoV-2 Variants of Concern Harboring Q677H

por Cong Zeng, John P. Evans, Julia N. Faraone, Panke Qu, Yi-Min Zheng, Linda Saif, Eugene M. Oltz, Gerard Lozanski, Richard J. Gumina, Shan-Lu Liu
Publicado 2021

A Novel <i>Toxoplasma</i> Inner Membrane Complex Suture-Associated Protein Regulates Suture Protein Targeting and Colocalizes with Membrane Trafficking Machinery

por Jessica H. Chern, Rebecca R. Pasquarelli, Andy S. Moon, Allan L. Chen, Jihui Sha, James A. Wohlschlegel, Peter J. Bradley
Publicado 2021

Genetic Analysis of the Salmonella FliE Protein That Forms the Base of the Flagellar Axial Structure

por Jordan J. Hendriksen, Hee Jung Lee, Alexander J. Bradshaw, Keiichi Namba, Fabienne F. V. Chevance, Tohru Minamino, Kelly T. Hughes
Publicado 2021

Interactions between Viral Regulatory Proteins Ensure an MOI-Independent Probability of Lysogeny during Infection by Bacteriophage P1

por Kailun Zhang, Kiara Pankratz, Hau Duong, Matthew Theodore, Jingwen Guan, Anxiao (Andrew) Jiang, Yiruo Lin, Lanying Zeng
Publicado 2021