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  1. 1261
    Dna2 processes behind the fork long ssDNA flaps generated by Pif1 and replication-dependent strand displacement
    “...DNA2 encodes a 5′ flap DNA endonuclease involved in replication and DNA double strand break...”
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  2. 1262
    In vivo base editing of post-mitotic sensory cells
    “... double-stranded DNA breaks or homology-directed repair, which is inefficient in postmitotic cells. Here...”
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  3. 1263
    Serine-linked PARP1 auto-modification controls PARP inhibitor response
    “...PARP inhibitors function by trapping PARP1 protein on DNA breaks, which has cytotoxic consequences...”
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  4. 1264
    Highly efficient RNA-guided base editing in rabbit
    “...Base editors can make targeted changes without inducing a double-stranded break. Here, the authors...”
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  5. 1265
    The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity
    “... the efficacy of 53BP1-mediated repair of DNA double-strand breaks (DSBs) by NHEJ....”
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  6. 1266
    Reciprocal regulation of RIG-I and XRCC4 connects DNA repair with RIG-I immune signaling
    “... and initiates IFN signaling, is recruited to double-stranded breaks and suppresses non-homologous end joining....”
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  7. 1267
    A multiscale 3D chemotaxis assay reveals bacterial navigation mechanisms
    por Marianne Grognot, Katja M. Taute
    Publicado 2021
    “.... crescentus breaks with the E. coli paradigm....”
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  8. 1268
    PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1
    “...Although loss of BRCA1 leads to defects in DNA double-strand break repair by homologous...”
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  9. 1269
    Modelling the ultra-strongly coupled spin-boson model with unphysical modes
    “... but experimental devices, and some natural systems, now operate in regimes where those methods break down. Lambert...”
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  10. 1270
    HPF1 remodels the active site of PARP1 to enable the serine ADP-ribosylation of histones
    “...Once DNA breaks occur, poly(ADP-ribose) polymerase 1 (PARP1) ADP-ribosylates itself and other DNA...”
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  11. 1271
    Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells
    “... at promoter regions by preventing DNA break accumulation....”
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  12. 1272
    EDITORIAL: Mercenaries and the media
    por David Robie
    Publicado 1997
    “... News breaks—or develops—on the Net these days with remarkable ease. News organisations are without...”
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  13. 1273
    Rad9/53BP1 promotes DNA repair via crossover recombination by limiting the Sgs1 and Mph1 helicases
    “... strand breaks. Here the authors reveal that Rad9 promotes long tract gene conversions, BIR and CO, during...”
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  14. 1274
    New records and updated distribution of Myopa metallica Camras 1992 (Diptera: Conopidae: Myopinae) in Chile by using integrative collection methods
    “... using citizen science. Our work breaks down the methodological barriers, providing a distribution for a...”
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  15. 1275
    Overestimation of the effect of climatic warming on spring phenology due to misrepresentation of chilling
    “... that many trees require to break winter dormancy. Here, the authors show that 7 of 12 current chilling...”
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  16. 1276
    Structural insights into two distinct binding modules for Lys63-linked polyubiquitin chains in RNF168
    “...E3 ubiquitin ligase RNF168 is important for the repair of DNA double-strand breaks and recognizes...”
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  17. 1277
    Transition path times of coupled folding and binding reveal the formation of an encounter complex
    “...How interactions between binding partners form or break is hidden in the transition paths from...”
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  18. 1278
    Zinc finger protein ZNF384 is an adaptor of Ku to DNA during classical non-homologous end-joining
    “... DNA double-strand breaks (DSBs) and maintain genome stability. Here the authors show that PARP1-driven...”
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  19. 1279
    Animal abuse: A close relationship with domestic violence
    por Gisele Kronhardt Scheffer
    Publicado 2019
    “... to break the cycle of abuse is education, with the consequent awareness of respect for life in all its...”
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  20. 1280
    Single-molecule level control of host-guest interactions in metallocycle-C60 complexes
    “... into their supramolecular interactions. Here, the authors use the scanning tunneling microscopy break junction technique...”
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