Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks

por Pauline Chanut, Sébastien Britton, Julia Coates, Stephen P. Jackson, Patrick Calsou
Publicado 2016

Correction: Corrigendum: Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks

por Pauline Chanut, Sébastien Britton, Julia Coates, Stephen P. Jackson, Patrick Calsou
Publicado 2017

Validating the concept of mutational signatures with isogenic cell models

por Xueqing Zou, Michel Owusu, Rebecca Harris, Stephen P. Jackson, Joanna I. Loizou, Serena Nik-Zainal
Publicado 2018

PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1

por Rimma Belotserkovskaya, Elisenda Raga Gil, Nicola Lawrence, Richard Butler, Gillian Clifford, Marcus D. Wilson, Stephen P. Jackson
Publicado 2020

MDC1 PST-repeat region promotes histone H2AX-independent chromatin association and DNA damage tolerance

por Israel Salguero, Rimma Belotserkovskaya, Julia Coates, Matylda Sczaniecka-Clift, Mukerrem Demir, Satpal Jhujh, Marcus D. Wilson, Stephen P. Jackson
Publicado 2019

Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia

por Martin Moder, Georgia Velimezi, Michel Owusu, Abdelghani Mazouzi, Marc Wiedner, Joana Ferreira da Silva, Lydia Robinson-Garcia, Fiorella Schischlik, Rastislav Slavkovsky, Robert Kralovics, Michael Schuster, Christoph Bock, Trey Ideker, Stephen P. Jackson, Jörg Menche, Joanna I. Loizou
Publicado 2017

Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48

por Georgia Velimezi, Lydia Robinson-Garcia, Francisco Muñoz-Martínez, Wouter W. Wiegant, Joana Ferreira da Silva, Michel Owusu, Martin Moder, Marc Wiedner, Sara Brin Rosenthal, Kathleen M. Fisch, Jason Moffat, Jörg Menche, Haico van Attikum, Stephen P. Jackson, Joanna I. Loizou
Publicado 2018

Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome

por Gabriel Balmus, Delphine Larrieu, Ana C. Barros, Casey Collins, Monica Abrudan, Mukerrem Demir, Nicola J. Geisler, Christopher J. Lelliott, Jacqueline K. White, Natasha A. Karp, James Atkinson, Andrea Kirton, Matt Jacobsen, Dean Clift, Raphael Rodriguez, Sanger Mouse Genetics Project, David J. Adams, Stephen P. Jackson
Publicado 2018

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

por Gabriel Balmus, Domenic Pilger, Julia Coates, Mukerrem Demir, Matylda Sczaniecka-Clift, Ana C. Barros, Michael Woods, Beiyuan Fu, Fengtang Yang, Elisabeth Chen, Matthias Ostermaier, Tatjana Stankovic, Hannes Ponstingl, Mareike Herzog, Kosuke Yusa, Francisco Munoz Martinez, Stephen T. Durant, Yaron Galanty, Petra Beli, David J. Adams, Allan Bradley, Emmanouil Metzakopian, Josep V. Forment, Stephen P. Jackson
Publicado 2019

Combinatorial CRISPR screen identifies fitness effects of gene paralogues

por Nicola A. Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona Behan, Emanuel Gonçalves, Anneliese Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco-Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams
Publicado 2021

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.

por Rebecca E McIntyre, Pavithra Lakshminarasimhan Chavali, Ozama Ismail, Damian M Carragher, Gabriela Sanchez-Andrade, Josep V Forment, Beiyuan Fu, Martin Del Castillo Velasco-Herrera, Andrew Edwards, Louise van der Weyden, Fengtang Yang, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis, Jeanne Estabel, Ferdia A Gallagher, Darren W Logan, Mark J Arends, Stephen H Tsang, Vinit B Mahajan, Cheryl L Scudamore, Jacqueline K White, Stephen P Jackson, Fanni Gergely, David J Adams
Publicado 2012