ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

par Gabriel Balmus, Domenic Pilger, Julia Coates, Mukerrem Demir, Matylda Sczaniecka-Clift, Ana C. Barros, Michael Woods, Beiyuan Fu, Fengtang Yang, Elisabeth Chen, Matthias Ostermaier, Tatjana Stankovic, Hannes Ponstingl, Mareike Herzog, Kosuke Yusa, Francisco Munoz Martinez, Stephen T. Durant, Yaron Galanty, Petra Beli, David J. Adams, Allan Bradley, Emmanouil Metzakopian, Josep V. Forment, Stephen P. Jackson
Publié 2019

Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.

par Rebecca E McIntyre, Pavithra Lakshminarasimhan Chavali, Ozama Ismail, Damian M Carragher, Gabriela Sanchez-Andrade, Josep V Forment, Beiyuan Fu, Martin Del Castillo Velasco-Herrera, Andrew Edwards, Louise van der Weyden, Fengtang Yang, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis, Jeanne Estabel, Ferdia A Gallagher, Darren W Logan, Mark J Arends, Stephen H Tsang, Vinit B Mahajan, Cheryl L Scudamore, Jacqueline K White, Stephen P Jackson, Fanni Gergely, David J Adams
Publié 2012

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer

par Mohammad Asim, Firas Tarish, Heather I. Zecchini, Kumar Sanjiv, Eleni Gelali, Charles E. Massie, Ajoeb Baridi, Anne Y. Warren, Wanfeng Zhao, Christoph Ogris, Leigh-Anne McDuffus, Patrice Mascalchi, Greg Shaw, Harveer Dev, Karan Wadhwa, Paul Wijnhoven, Josep V. Forment, Scott R. Lyons, Andy G. Lynch, Cormac O’Neill, Vincent R. Zecchini, Paul S. Rennie, Aria Baniahmad, Simon Tavaré, Ian G. Mills, Yaron Galanty, Nicola Crosetto, Niklas Schultz, David Neal, Thomas Helleday
Publié 2017