MDC1 PST-repeat region promotes histone H2AX-independent chromatin association and DNA damage tolerance

por Israel Salguero, Rimma Belotserkovskaya, Julia Coates, Matylda Sczaniecka-Clift, Mukerrem Demir, Satpal Jhujh, Marcus D. Wilson, Stephen P. Jackson
Publicado 2019

Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome

por Gabriel Balmus, Delphine Larrieu, Ana C. Barros, Casey Collins, Monica Abrudan, Mukerrem Demir, Nicola J. Geisler, Christopher J. Lelliott, Jacqueline K. White, Natasha A. Karp, James Atkinson, Andrea Kirton, Matt Jacobsen, Dean Clift, Raphael Rodriguez, Sanger Mouse Genetics Project, David J. Adams, Stephen P. Jackson
Publicado 2018

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

por Gabriel Balmus, Domenic Pilger, Julia Coates, Mukerrem Demir, Matylda Sczaniecka-Clift, Ana C. Barros, Michael Woods, Beiyuan Fu, Fengtang Yang, Elisabeth Chen, Matthias Ostermaier, Tatjana Stankovic, Hannes Ponstingl, Mareike Herzog, Kosuke Yusa, Francisco Munoz Martinez, Stephen T. Durant, Yaron Galanty, Petra Beli, David J. Adams, Allan Bradley, Emmanouil Metzakopian, Josep V. Forment, Stephen P. Jackson
Publicado 2019