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  1. 22761
    Oral and Oropharyngeal Squamous Cell Carcinoma in Our Population: The Clinic-Pathological and Morphological Description of 153 Cases
    “...Oral cavity and oropharynx are one of the commonest sites for cancers in our population due to a...”
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  2. 22762
    Mild replication stress causes chromosome mis-segregation via premature centriole disengagement
    “..., the authors show that inducing mild replication stress in cancerous and non-cancerous cell lines leads...”
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  3. 22763
    Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas
    “...It is known that invasive lung adenocarcinomas evolve from pre-cancerous dysplastic lesions...”
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  4. 22764
    Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment
    por Hua Sun, Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl, Sherri R. Davies, Matthew H. Bailey, Tina M. Primeau, Jeremy Hoog, Jacqueline L. Mudd, Dennis A. Dean, Rajesh Patidar, Li Chen, Matthew A. Wyczalkowski, Reyka G. Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian A. Van Tine, Cynthia X. Ma, Rebecca Aft, Katherine C. Fuh, Julie K. Schwarz, Jose P. Zevallos, Sidharth V. Puram, John F. Dipersio, The NCI PDXNet Consortium, Brandi Davis-Dusenbery, Matthew J. Ellis, Michael T. Lewis, Michael A. Davies, Meenhard Herlyn, Bingliang Fang, Jack A. Roth, Alana L. Welm, Bryan E. Welm, Funda Meric-Bernstam, Feng Chen, Ryan C. Fields, Shunqiang Li, Ramaswamy Govindan, James H. Doroshow, Jeffrey A. Moscow, Yvonne A. Evrard, Jeffrey H. Chuang, Benjamin J. Raphael, Li Ding
    Publicado 2021
    “... and clinical features of cancers. Here the authors present a cohort of 536 PDX models from 25 cancers, as well...”
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  5. 22765
    Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma
    “..., preinvasive, minimally invasive or sometimes invasive lung cancers. Here, Hu et al. perform multi-region exome...”
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  6. 22766
    Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours
    “...Several breast cancers may originate from mammary luminal cells and inactivating mutations of p53...”
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  7. 22767
    METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N 6-methyladenosine-dependent YTHDF binding
    “... in cancers is unclear. Here the authors show that N6-methyladenosine methylation writer METTL3 downregulates...”
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  8. 22768
    CK2 Phosphorylation of Human Papillomavirus 16 E2 on Serine 23 Promotes Interaction with TopBP1 and Is Critical for E2 Interaction with Mitotic Chromatin and the Viral Life Cycle
    “... Human papillomaviruses are causative agents in around 5% of all cancers, with no specific...”
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  9. 22769
    Prognostic role of microRNA-181a/b in hematological malignancies: a meta-analysis.
    “... as tumor suppressors or oncogenes, and have prognostic value for patients with cancers. In recent years...”
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  10. 22770
    Identification of the kinase STK25 as an upstream activator of LATS signaling
    “...Hippo pathway inactivation plays a role in many cancers, although how tumor cells depress signaling...”
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  11. 22771
    Aging-associated distinctive DNA methylation changes of LINE-1 retrotransposons in pure cell-free DNA from human blood
    “... originates mainly in apoptotic, senescent and cancerous cells, this approach allows efficient analysis...”
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  12. 22772
    Post-Transplant Malignancies following Pancreas Transplantation: Incidence and Implications on Long-Term Outcome from a Single-Center Perspective
    “...%) developed skin cancers (four patients with melanoma, 32 with NMSCs). Solid organ malignancy occurred in 25...”
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  13. 22773
    Solitary Pulmonary Inflammatory Nodule: CT Features and Pathological Findings
    por Xiao YD, Lv FJ, Li WJ, Fu BJ, Lin RY, Chu ZG
    Publicado 2021
    “... and lung cancerous nodules were enrolled from January 2013 to December 2020. Nodules were classified...”
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  14. 22774
    MYCN amplification and ATRX mutations are incompatible in neuroblastoma
    “...In most cancers, mutations that lead to oncogene activation and tumor suppressor inactivation...”
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  15. 22775
    A canine chimeric monoclonal antibody targeting PD-L1 and its clinical efficacy in canine oral malignant melanoma or undifferentiated sarcoma
    “... when it binds to its ligand, PD-L1. Aberrant PD-L1 expression is reported in various human cancers...”
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  16. 22776
    Incidence of omental metastasis in uterine serous carcinoma: study protocol for a systematic review and meta-analysis
    “...Introduction Uterine serous carcinoma accounts for only about 10% of all endometrial cancers...”
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  17. 22777
    Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action
    “...HER2 acts an oncogenic driver in numerous cancers. Here, the authors design an anti-HER2...”
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  18. 22778
    Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro
    “...Mismatch repair (MMR)-deficient cancers are characterized by microsatellite instability (MSI...”
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  19. 22779
    Microenvironment meets lineage complexity in junctional tumorigenesis
    por Wa Xian, Frank McKeon
    Publicado 2019
    “... be pharmacologically dampened to reduce the onset of cancers....”
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  20. 22780
    Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas
    “...Cutaneous gamma-delta T cell lymphomas are rare but aggressive cancers. Here, by DNA, RNA...”
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