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22761“...Oral cavity and oropharynx are one of the commonest sites for cancers in our population due to a...”
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22762por Therese Wilhelm, Anna-Maria Olziersky, Daniela Harry, Filipe De Sousa, Helène Vassal, Anja Eskat, Patrick Meraldi“..., the authors show that inducing mild replication stress in cancerous and non-cancerous cell lines leads...”
Publicado 2019
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22763por Xin Hu, Marcos R. Estecio, Runzhe Chen, Alexandre Reuben, Linghua Wang, Junya Fujimoto, Jian Carrot-Zhang, Nicholas McGranahan, Lisha Ying, Junya Fukuoka, Chi-Wan Chow, Hoa H. N. Pham, Myrna C. B. Godoy, Brett W. Carter, Carmen Behrens, Jianhua Zhang, Mara B. Antonoff, Boris Sepesi, Yue Lu, Harvey I. Pass, Humam Kadara, Paul Scheet, Ara A. Vaporciyan, John V. Heymach, Ignacio I. Wistuba, J. Jack Lee, P. Andrew Futreal, Dan Su, Jean-Pierre J. Issa, Jianjun Zhang“...It is known that invasive lung adenocarcinomas evolve from pre-cancerous dysplastic lesions...”
Publicado 2021
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22764por Hua Sun, Song Cao, R. Jay Mashl, Chia-Kuei Mo, Simone Zaccaria, Michael C. Wendl, Sherri R. Davies, Matthew H. Bailey, Tina M. Primeau, Jeremy Hoog, Jacqueline L. Mudd, Dennis A. Dean, Rajesh Patidar, Li Chen, Matthew A. Wyczalkowski, Reyka G. Jayasinghe, Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Yize Li, Kian-Huat Lim, Andrea Wang-Gillam, Brian A. Van Tine, Cynthia X. Ma, Rebecca Aft, Katherine C. Fuh, Julie K. Schwarz, Jose P. Zevallos, Sidharth V. Puram, John F. Dipersio, The NCI PDXNet Consortium, Brandi Davis-Dusenbery, Matthew J. Ellis, Michael T. Lewis, Michael A. Davies, Meenhard Herlyn, Bingliang Fang, Jack A. Roth, Alana L. Welm, Bryan E. Welm, Funda Meric-Bernstam, Feng Chen, Ryan C. Fields, Shunqiang Li, Ramaswamy Govindan, James H. Doroshow, Jeffrey A. Moscow, Yvonne A. Evrard, Jeffrey H. Chuang, Benjamin J. Raphael, Li Ding“... and clinical features of cancers. Here the authors present a cohort of 536 PDX models from 25 cancers, as well...”
Publicado 2021
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22765por Xin Hu, Junya Fujimoto, Lisha Ying, Junya Fukuoka, Kazuto Ashizawa, Wenyong Sun, Alexandre Reuben, Chi-Wan Chow, Nicholas McGranahan, Runzhe Chen, Jinlin Hu, Myrna C. Godoy, Kazuhiro Tabata, Kishio Kuroda, Lei Shi, Jun Li, Carmen Behrens, Edwin Roger Parra, Latasha D. Little, Curtis Gumbs, Xizeng Mao, Xingzhi Song, Samantha Tippen, Rebecca L. Thornton, Humam Kadara, Paul Scheet, Emily Roarty, Edwin Justin Ostrin, Xu Wang, Brett W. Carter, Mara B. Antonoff, Jianhua Zhang, Ara A. Vaporciyan, Harvey Pass, Stephen G. Swisher, John V. Heymach, J. Jack Lee, Ignacio I. Wistuba, Waun Ki Hong, P. Andrew Futreal, Dan Su, Jianjun Zhang“..., preinvasive, minimally invasive or sometimes invasive lung cancers. Here, Hu et al. perform multi-region exome...”
Publicado 2019
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22766“...Several breast cancers may originate from mammary luminal cells and inactivating mutations of p53...”
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22767por Wei Wang, Fei Shao, Xueying Yang, Juhong Wang, Rongxuan Zhu, Yannan Yang, Gaoxiang Zhao, Dong Guo, Yingli Sun, Jie Wang, Qi Xue, Shugeng Gao, Yibo Gao, Jie He, Zhimin Lu“... in cancers is unclear. Here the authors show that N6-methyladenosine methylation writer METTL3 downregulates...”
Publicado 2021
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22768por Apurva T. Prabhakar, Claire D. James, Dipon Das, Raymonde Otoa, Matthew Day, John Burgner, Christian T. Fontan, Xu Wang, Sarah H. Glass, Andreas Wieland, Mary M. Donaldson, Molly L. Bristol, Renfeng Li, Anthony W. Oliver, Laurence H. Pearl, Brian O. Smith, Iain M. Morgan“... Human papillomaviruses are causative agents in around 5% of all cancers, with no specific...”
Publicado 2021
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22769por Shenglong Lin, Lili Pan, Shicheng Guo, Junjie Wu, Li Jin, Jiu-Cun Wang, Shaoyuan Wang“... as tumor suppressors or oncogenes, and have prognostic value for patients with cancers. In recent years...”
Publicado 2013
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22770por Sanghee Lim, Nicole Hermance, Tenny Mudianto, Hatim M. Mustaly, Ian Paolo Morelos Mauricio, Marc A. Vittoria, Ryan J. Quinton, Brian W. Howell, Hauke Cornils, Amity L. Manning, Neil J. Ganem“...Hippo pathway inactivation plays a role in many cancers, although how tumor cells depress signaling...”
Publicado 2019
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22771por Wardah Mahmood, Lars Erichsen, Pauline Ott, Wolfgang A. Schulz, Johannes C. Fischer, Marcos J. Arauzo-Bravo, Marcelo L. Bendhack, Mohamed Hassan, Simeon Santourlidis“... originates mainly in apoptotic, senescent and cancerous cells, this approach allows efficient analysis...”
Publicado 2020
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22772por Felix J. Krendl, Franka Messner, Claudia Bösmüller, Stefan Scheidl, Benno Cardini, Thomas Resch, Annemarie Weissenbacher, Rupert Oberhuber, Manuel Maglione, Stefan Schneeberger, Dietmar Öfner, Christian Margreiter“...%) developed skin cancers (four patients with melanoma, 32 with NMSCs). Solid organ malignancy occurred in 25...”
Publicado 2021
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22773“... and lung cancerous nodules were enrolled from January 2013 to December 2020. Nodules were classified...”
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22774por Maged Zeineldin, Sara Federico, Xiang Chen, Yiping Fan, Beisi Xu, Elizabeth Stewart, Xin Zhou, Jongrye Jeon, Lyra Griffiths, Rosa Nguyen, Jackie Norrie, John Easton, Heather Mulder, Donald Yergeau, Yanling Liu, Jianrong Wu, Collin Van Ryn, Arlene Naranjo, Michael D. Hogarty, Marcin M. Kamiński, Marc Valentine, Shondra M. Pruett-Miller, Alberto Pappo, Jinghui Zhang, Michael R. Clay, Armita Bahrami, Peter Vogel, Seungjae Lee, Anang Shelat, Jay F. Sarthy, Michael P. Meers, Rani E. George, Elaine R. Mardis, Richard K. Wilson, Steven Henikoff, James R. Downing, Michael A. Dyer“...In most cancers, mutations that lead to oncogene activation and tumor suppressor inactivation...”
Publicado 2020
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22775por Naoya Maekawa, Satoru Konnai, Satoshi Takagi, Yumiko Kagawa, Tomohiro Okagawa, Asami Nishimori, Ryoyo Ikebuchi, Yusuke Izumi, Tatsuya Deguchi, Chie Nakajima, Yukinari Kato, Keiichi Yamamoto, Hidetoshi Uemura, Yasuhiko Suzuki, Shiro Murata, Kazuhiko Ohashi“... when it binds to its ligand, PD-L1. Aberrant PD-L1 expression is reported in various human cancers...”
Publicado 2017
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22776por Yu Xu, Yu Cheng, Lin-Lin Zhang, Cui Hu, Fei-Xue Xue, Ya Jia, Qin Zhao-Juan, Du Yi, Zhang Qian-Wen, He Yue-Dong, Zheng Ai“...Introduction Uterine serous carcinoma accounts for only about 10% of all endometrial cancers...”
Publicado 2021
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22777por Florian Kast, Martin Schwill, Jakob C. Stüber, Svende Pfundstein, Gabriela Nagy-Davidescu, Josep M. Monné Rodríguez, Frauke Seehusen, Christian P. Richter, Annemarie Honegger, Karen Patricia Hartmann, Thomas G. Weber, Felix Kroener, Patrick Ernst, Jacob Piehler, Andreas Plückthun“...HER2 acts an oncogenic driver in numerous cancers. Here, the authors design an anti-HER2...”
Publicado 2021
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22778por Yusuke Matsuno, Yuko Atsumi, Atsuhiro Shimizu, Kotoe Katayama, Haruka Fujimori, Mai Hyodo, Yusuke Minakawa, Yoshimichi Nakatsu, Syuzo Kaneko, Ryuji Hamamoto, Teppei Shimamura, Satoru Miyano, Teruhisa Tsuzuki, Fumio Hanaoka, Ken-ichi Yoshioka“...Mismatch repair (MMR)-deficient cancers are characterized by microsatellite instability (MSI...”
Publicado 2019
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22779
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22780por Jay Daniels, Peter G. Doukas, Maria E. Martinez Escala, Kimberly G. Ringbloom, David J. H. Shih, Jingyi Yang, Kyle Tegtmeyer, Joonhee Park, Jane J. Thomas, Mehmet E. Selli, Can Altunbulakli, Ragul Gowthaman, Samuel H. Mo, Balaji Jothishankar, David R. Pease, Barbara Pro, Farah R. Abdulla, Christopher Shea, Nidhi Sahni, Alejandro A. Gru, Brian G. Pierce, Abner Louissaint, Joan Guitart, Jaehyuk Choi“...Cutaneous gamma-delta T cell lymphomas are rare but aggressive cancers. Here, by DNA, RNA...”
Publicado 2020
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