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  1. 17961
    Broad genic repression domains signify enhanced silencing of oncogenes
    “...Epigenetically altered genes can have a key role in cancer pathobiology but epigenetic signatures...”
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  2. 17962
    Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease
    “...Multiple myeloma is a cancer of the bone marrow that can induce bone disease. Here, the authors...”
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  3. 17963
    Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL
    “...Aberrant protein translation and uncontrolled lipid metabolism are hallmarks of cancer growth. Here...”
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  4. 17964
    Single-breath-hold photoacoustic computed tomography of the breast
    “...The current standard for breast cancer diagnostic is a mammogram; however, the sensitivity...”
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  5. 17965
    Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma
    “...One cause of relapse in cancer patients treated with chimeric antigen receptor (CAR) T cells...”
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  6. 17966
    Microenvironment-derived factors driving metastatic plasticity in melanoma
    “...Phenotype switching is a form of plasticity that allows melanoma cancer cells that leave...”
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  7. 17967
    Dual-mechanism based CTLs infiltration enhancement initiated by Nano-sapper potentiates immunotherapy against immune-excluded tumors
    “... can enhance T cell infiltration in a mouse model of pancreatic cancer....”
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  8. 17968
    BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis
    “...Breast cancer amplified sequence 2 (BCAS2) is involved in pre-mRNA splicing but its physiological...”
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  9. 17969
    Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
    “... cancer (TNBC) but the underlying proteome profiles are unknown. Here, the authors characterize...”
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  10. 17970
    Metas-Chip precisely identifies presence of micrometastasis in live biopsy samples by label free approach
    “...Detecting metastatic cells in tumor/lymph node samples of breast cancer patients is extremely...”
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  11. 17971
    Asymmetric localization of DLC1 defines avian trunk neural crest polarity for directional delamination and migration
    “... in liver cancer 1, is asymmetrically localized in the cytoplasm, governing neural crest migratory...”
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  12. 17972
    H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis
    “...Histone modifications play important roles in gene transcription and cancer. Here the authors...”
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  13. 17973
    TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism
    “...The PI3K/AKT signalling pathway regulates cancer metabolism. Here, the authors show a reciprocal...”
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  14. 17974
    Fibronectin-guided migration of carcinoma collectives
    “...Tumour microenvironment influences the migration of cancer cells. Here the authors analyse...”
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  15. 17975
    Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis
    “... development, lymphomagenesis and cancer cell survival....”
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  16. 17976
    ABCB1 protects bat cells from DNA damage induced by genotoxic compounds
    “...Bats possess an extended lifespan compared to most mammals of their size, and have a low cancer...”
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  17. 17977
    WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation
    “... degradation, thus functioning as a tumour suppressor in liver cancer...”
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  18. 17978
    Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor
    “... cancers that has been implicated in drug resistance. Here the authors identify a small molecule inhibitor...”
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  19. 17979
    Identification of pyrazolopyridazinones as PDEδ inhibitors
    “... inhibitor of KRAS-dependent cancer cell growth with low cytotoxic side effects....”
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  20. 17980
    Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin
    “... underlying such regulation and the relevance to cancer development are unknown. Here, Fusté et al. show...”
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