Phosphorylation of KasB regulates virulence and acid-fastness in Mycobacterium tuberculosis.

por Catherine Vilchèze, Virginie Molle, Séverine Carrère-Kremer, Jade Leiba, Lionel Mourey, Shubhada Shenai, Grégory Baronian, Joann Tufariello, Travis Hartman, Romain Veyron-Churlet, Xavier Trivelli, Sangeeta Tiwari, Brian Weinrick, David Alland, Yann Guérardel, William R Jacobs, Laurent Kremer
Publicado 2014

A pathogen type III effector with a novel E3 ubiquitin ligase architecture.

por Alexander U Singer, Sebastian Schulze, Tatiana Skarina, Xiaohui Xu, Hong Cui, Lennart Eschen-Lippold, Monique Egler, Tharan Srikumar, Brian Raught, Justin Lee, Dierk Scheel, Alexei Savchenko, Ulla Bonas
Publicado 2013

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease.

por Kiira Ratia, Andrew Kilianski, Yahira M Baez-Santos, Susan C Baker, Andrew Mesecar
Publicado 2014

The secreted triose phosphate isomerase of Brugia malayi is required to sustain microfilaria production in vivo.

por James P Hewitson, Dominik Rückerl, Yvonne Harcus, Janice Murray, Lauren M Webb, Simon A Babayan, Judith E Allen, Agnes Kurniawan, Rick M Maizels
Publicado 2014

Foxp3⁺ regulatory T cells delay expulsion of intestinal nematodes by suppression of IL-9-driven mast cell activation in BALB/c but not in C57BL/6 mice.

por Birte Blankenhaus, Martina Reitz, Yannick Brenz, Marie-Luise Eschbach, Wiebke Hartmann, Irma Haben, Tim Sparwasser, Jochen Huehn, Anja Kühl, Thorsten B Feyerabend, Hans-Reimer Rodewald, Minka Breloer
Publicado 2014

Viral enhancer mimicry of host innate-immune promoters.

por Kai A Kropp, Ana Angulo, Peter Ghazal
Publicado 2014

An anti-human ICAM-1 antibody inhibits rhinovirus-induced exacerbations of lung inflammation.

por Stephanie Traub, Alexandra Nikonova, Alan Carruthers, Rebecca Dunmore, Katherine A Vousden, Leila Gogsadze, Weidong Hao, Qing Zhu, Katie Bernard, Jie Zhu, Michael Dymond, Gary R McLean, Ross P Walton, Nicholas Glanville, Alison Humbles, Musa Khaitov, Ted Wells, Roland Kolbeck, Andrew J Leishman, Matthew A Sleeman, Nathan W Bartlett, Sebastian L Johnston
Publicado 2013

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity.

por Marianne Lucas-Hourani, Daniel Dauzonne, Pierre Jorda, Gaëlle Cousin, Alexandru Lupan, Olivier Helynck, Grégory Caignard, Geneviève Janvier, Gwénaëlle André-Leroux, Samira Khiar, Nicolas Escriou, Philippe Desprès, Yves Jacob, Hélène Munier-Lehmann, Frédéric Tangy, Pierre-Olivier Vidalain
Publicado 2013

Epigenetic changes modulate schistosome egg formation and are a novel target for reducing transmission of schistosomiasis.

por Vitor Coutinho Carneiro, Isabel Caetano de Abreu da Silva, Eduardo José Lopes Torres, Stephany Caby, Julien Lancelot, Mathieu Vanderstraete, Silviya D Furdas, Manfred Jung, Raymond J Pierce, Marcelo Rosado Fantappié
Publicado 2014

Genetic dissection of Anopheles gambiae gut epithelial responses to Serratia marcescens.

por Stavros Stathopoulos, Daniel E Neafsey, Mara K N Lawniczak, Marc A T Muskavitch, George K Christophides
Publicado 2014

Emerging and emerged pathogenic Candida species: beyond the Candida albicans paradigm.

por Nicolas Papon, Vincent Courdavault, Marc Clastre, Richard J Bennett
Publicado 2013

Neutrophil-derived IL-1β is sufficient for abscess formation in immunity against Staphylococcus aureus in mice.

por John S Cho, Yi Guo, Romela Irene Ramos, Frank Hebroni, Seema B Plaisier, Caiyun Xuan, Jennifer L Granick, Hironori Matsushima, Akira Takashima, Yoichiro Iwakura, Ambrose L Cheung, Genhong Cheng, Delphine J Lee, Scott I Simon, Lloyd S Miller
Publicado 2012

In vivo ligands of MDA5 and RIG-I in measles virus-infected cells.

por Simon Runge, Konstantin M J Sparrer, Charlotte Lässig, Katharina Hembach, Alina Baum, Adolfo García-Sastre, Johannes Söding, Karl-Klaus Conzelmann, Karl-Peter Hopfner
Publicado 2014

IL-4Rα-associated antigen processing by B cells promotes immunity in Nippostrongylus brasiliensis infection.

por William G C Horsnell, Matthew G Darby, Jennifer C Hoving, Natalie Nieuwenhuizen, Henry J McSorley, Hlumani Ndlovu, Saeeda Bobat, Matti Kimberg, Frank Kirstein, Anthony J Cutler, Benjamin Dewals, Adam F Cunningham, Frank Brombacher
Publicado 2013

Caspase-1 promotes Epstein-Barr virus replication by targeting the large tegument protein deneddylase to the nucleus of productively infected cells.

por Stefano Gastaldello, Xinsong Chen, Simone Callegari, Maria G Masucci
Publicado 2013

Discovery of a siderophore export system essential for virulence of Mycobacterium tuberculosis.

por Ryan M Wells, Christopher M Jones, Zhaoyong Xi, Alexander Speer, Olga Danilchanka, Kathryn S Doornbos, Peibei Sun, Fangming Wu, Changlin Tian, Michael Niederweis
Publicado 2013

Transcription factor Amr1 induces melanin biosynthesis and suppresses virulence in Alternaria brassicicola.

por Yangrae Cho, Akhil Srivastava, Robin A Ohm, Christopher B Lawrence, Koon-Hui Wang, Igor V Grigoriev, Sharadchandra P Marahatta
Publicado 2012

Intact type I Interferon production and IRF7 function in sooty mangabeys.

por Steven E Bosinger, Zachary P Johnson, Kathryn A Folkner, Nirav Patel, Tayebeh Hashempour, Simon P Jochems, Perla M Del Rio Estrada, Mirko Paiardini, Rongtuan Lin, Thomas H Vanderford, John Hiscott, Guido Silvestri
Publicado 2013

Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth.

por Sarah A Stanley, Amy K Barczak, Melanie R Silvis, Samantha S Luo, Kimberly Sogi, Martha Vokes, Mark-Anthony Bray, Anne E Carpenter, Christopher B Moore, Noman Siddiqi, Eric J Rubin, Deborah T Hung
Publicado 2014

Serotonergic chemosensory neurons modify the C. elegans immune response by regulating G-protein signaling in epithelial cells.

por Alexandra Anderson, Henry Laurenson-Schafer, Frederick A Partridge, Jonathan Hodgkin, Rachel McMullan
Publicado 2013