PDGF receptor-α does not promote HCMV entry into epithelial and endothelial cells but increased quantities stimulate entry by an abnormal pathway.

por Adam L Vanarsdall, Todd W Wisner, Hetian Lei, Andrius Kazlauskas, David C Johnson
Publicado 2012

IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals.

por Ana Villegas-Mendez, J Brian de Souza, Seen-Wai Lavelle, Emily Gwyer Findlay, Tovah N Shaw, Nico van Rooijen, Christiaan J Saris, Christopher A Hunter, Eleanor M Riley, Kevin N Couper
Publicado 2013

Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress.

por Christine R Collins, Fiona Hackett, Malcolm Strath, Maria Penzo, Chrislaine Withers-Martinez, David A Baker, Michael J Blackman
Publicado 2013

Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A).

por Birgitte P S Jacky, Patton E Garay, Jérôme Dupuy, Jeremy B Nelson, Brian Cai, Yanira Molina, Joanne Wang, Lance E Steward, Ron S Broide, Joseph Francis, K Roger Aoki, Raymond C Stevens, Ester Fernández-Salas
Publicado 2013

A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model.

por Iart Luca Shytaj, Sandro Norelli, Barbara Chirullo, Alessandro Della Corte, Matt Collins, Jake Yalley-Ogunro, Jack Greenhouse, Nunzio Iraci, Edward P Acosta, Maria Letizia Barreca, Mark G Lewis, Andrea Savarino
Publicado 2012

Polyfunctional type-1, -2, and -17 CD8⁺ T cell responses to apoptotic self-antigens correlate with the chronic evolution of hepatitis C virus infection.

por Debora Franceschini, Paola Del Porto, Silvia Piconese, Emanuele Trella, Daniele Accapezzato, Marino Paroli, Stefania Morrone, Enza Piccolella, Enea Spada, Alfonso Mele, John Sidney, Alessandro Sette, Vincenzo Barnaba
Publicado 2012

Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity.

por Annalisa Bianco, Veronica Reghellin, Lorena Donnici, Simone Fenu, Reinaldo Alvarez, Chiara Baruffa, Francesco Peri, Massimiliano Pagani, Sergio Abrignani, Petra Neddermann, Raffaele De Francesco
Publicado 2012

The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cells.

por Ildar Gabaev, Lars Steinbrück, Claudia Pokoyski, Andreas Pich, Richard J Stanton, Reinhard Schwinzer, Thomas F Schulz, Roland Jacobs, Martin Messerle, Penelope C Kay-Fedorov
Publicado 2011

Multilocus sequence typing as a replacement for serotyping in Salmonella enterica.

por Mark Achtman, John Wain, François-Xavier Weill, Satheesh Nair, Zhemin Zhou, Vartul Sangal, Mary G Krauland, James L Hale, Heather Harbottle, Alexandra Uesbeck, Gordon Dougan, Lee H Harrison, Sylvain Brisse, S. Enterica MLST Study Group
Publicado 2012

Induction of GADD34 is necessary for dsRNA-dependent interferon-β production and participates in the control of Chikungunya virus infection.

por Giovanna Clavarino, Nuno Cláudio, Thérèse Couderc, Alexandre Dalet, Delphine Judith, Voahirana Camosseto, Enrico K Schmidt, Till Wenger, Marc Lecuit, Evelina Gatti, Philippe Pierre
Publicado 2012

Legionella pneumophila secretes a mitochondrial carrier protein during infection.

por Pavel Dolezal, Margareta Aili, Janette Tong, Jhih-Hang Jiang, Carlo M T Marobbio, Sau Fung Lee, Ralf Schuelein, Simon Belluzzo, Eva Binova, Aurelie Mousnier, Gad Frankel, Giulia Giannuzzi, Ferdinando Palmieri, Kipros Gabriel, Thomas Naderer, Elizabeth L Hartland, Trevor Lithgow
Publicado 2012

A new evolutionary model for hepatitis C virus chronic infection.

por Rebecca R Gray, Marco Salemi, Paul Klenerman, Oliver G Pybus
Publicado 2012

TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility.

por Marie Chaussepied, Natacha Janski, Martin Baumgartner, Regina Lizundia, Kirsty Jensen, William Weir, Brian R Shiels, Jonathan B Weitzman, Elizabeth J Glass, Dirk Werling, Gordon Langsley
Publicado 2010

Viral retasking of hBre1/RNF20 to recruit hPaf1 for transcriptional activation.

por Gregory J Fonseca, Michael J Cohen, Anthony C Nichols, John W Barrett, Joe S Mymryk
Publicado 2013

Structural basis of cytotoxicity mediated by the type III secretion toxin ExoU from Pseudomonas aeruginosa.

por Claire Gendrin, Carlos Contreras-Martel, Stéphanie Bouillot, Sylvie Elsen, David Lemaire, Dimitrios A Skoufias, Philippe Huber, Ina Attree, Andréa Dessen
Publicado 2012

Dengue virus targets the adaptor protein MITA to subvert host innate immunity.

por Chia-Yi Yu, Tsung-Hsien Chang, Jian-Jong Liang, Ruei-Lin Chiang, Yi-Ling Lee, Ching-Len Liao, Yi-Ling Lin
Publicado 2012

Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios.

por Wai-Leung Ng, Lark Perez, Jianping Cong, Martin F Semmelhack, Bonnie L Bassler
Publicado 2012

Systematic review of mucosal immunity induced by oral and inactivated poliovirus vaccines against virus shedding following oral poliovirus challenge.

por Thomas R Hird, Nicholas C Grassly
Publicado 2012

LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells.

por Selinda J Orr, Ashley R Burg, Tim Chan, Laura Quigley, Gareth W Jones, Jill W Ford, Deborah Hodge, Catherine Razzook, Joseph Sarhan, Yava L Jones, Gillian C Whittaker, Kimberly C Boelte, Lyudmila Lyakh, Marco Cardone, Geraldine M O'Connor, Cuiyan Tan, Hongchuan Li, Stephen K Anderson, Simon A Jones, Weiguo Zhang, Philip R Taylor, Giorgio Trinchieri, Daniel W McVicar
Publicado 2013

Glycan masking of Plasmodium vivax Duffy Binding Protein for probing protein binding function and vaccine development.

por Sowmya Sampath, Chris Carrico, Joel Janes, Sairam Gurumoorthy, Claire Gibson, Martin Melcher, Chetan E Chitnis, Ruobing Wang, William R Schief, Joseph D Smith
Publicado 2013