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  1. 661
    Involvement of serotonergic, noradrenergic and gabaergic systems in the antinociceptive effect of a ketamine-magnesium sulfate combination in acute pain
    “...Ketamine and magnesium can interact in additive, supra-additive and antagonistic manners...”
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  2. 662
    Research on Highly Pathogenic H5N1 Influenza Virus: The Way Forward
    por Anthony S. Fauci
    Publicado 2012
    “..., including the general public, and all decisions regarding such research must be made in a transparent manner....”
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  3. 663
    Molecular variation in a functionally divergent homolog of FCA regulates flowering time in Arabidopsis thaliana
    “... homolog of Flowering Control Locus A (FCA) functions in an antagonistic manner to FCA in regulating...”
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  4. 664
    Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants
    “... manner....”
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  5. 665
    reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4+ memory T cells
    “... in an unbiased genome-wide manner....”
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  6. 666
    Dipole states and coherent interaction in surface-acoustic-wave coupled phononic resonators
    “... and coupled mechanical resonators, allowing in a reciprocal manner to coherently control the resonator motion...”
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  7. 667
    Identification of the kinase STK25 as an upstream activator of LATS signaling
    “... is unclear. Here, Lim et al. identify STK25, which activates LATS in a manner distinct from other upstream...”
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  8. 668
    Structural insights into the mechanism of rhodopsin phosphodiesterase
    “...Rhodopsin phosphodiesterase (Rh-PDE) hydrolyzes both cAMP and cGMP in a light-dependent manner...”
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  9. 669
    Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation
    “... metal-dependent manner and constitutes a founding member of a new carbohydrate esterase family....”
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  10. 670
    Electrotunable liquid sulfur microdroplets
    “... cell and tune its characteristics in a fast, repeatable, and controlled manner....”
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  11. 671
    Color-tunable single-fluorophore supramolecular system with assembly-encoded emission
    “...Regulating fluorescent properties of small molecules in a controlled manner has been a fundamental...”
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  12. 672
    A structural model of flagellar filament switching across multiple bacterial species
    “... switch between different supercoiled states in a highly cooperative manner. Here the authors present near...”
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  13. 673
    Expression of CD226 is associated to but not required for NK cell education
    “...CD226 is an activating receptor expressed in a co-varied manner with inhibitory receptors...”
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  14. 674
    Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone
    “... DNA in an ATP-hydrolysis-dependent manner, and present the cryo-EM structure of an ATAD2 family ATPase...”
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  15. 675
    Synchrotron phase-contrast microtomography of coprolites generates novel palaeobiological data
    “... by classical techniques of investigation, which cannot find and image the inclusions in an adequate manner. We...”
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  16. 676
    DNA origami single crystals with Wulff shapes
    “...DNA origami is a valuable tool for precise manipulation of molecules in a three dimensional manner...”
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  17. 677
    CircGRIA1 shows an age-related increase in male macaque brain and regulates synaptic plasticity and synaptogenesis
    “... the authors show the circGRIA1 is expressed in an age-dependent manner in the male macaque brain and serves a...”
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  18. 678
    OTUD5 cooperates with TRIM25 in transcriptional regulation and tumor progression via deubiquitination activity
    “... TRIM25 dependent manner, which in turn controls the expression of tumour suppressor protein, PML....”
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  19. 679
    The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway
    “... PTEN/PI3K-independent manner by regulating DEPTOR stability via inhibition of KDM4A activity....”
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  20. 680
    Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium
    “... requirements for the AF1 and AF2 domains of the ERα, and ERα acts in a biphasic manner dependent...”
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