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  1. 14401
    Discovering Functions of Unannotated Genes from a Transcriptome Survey of Wild Fungal Isolates
    “... architecture, and a gene that mediated amino acid starvation resistance. These findings validate the power...”
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  2. 14402
    Allosteric Activation of Bacterial Response Regulators: the Role of the Cognate Histidine Kinase Beyond Phosphorylation
    “... mediate key signaling pathways that allow bacteria to integrate extra- or intracellular signals. Here we...”
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  3. 14403
    Functional Analysis of Rhomboid Proteases during <italic toggle="yes">Toxoplasma</italic> Invasion
    “... transmembrane adhesins that mediate binding to receptors on the substrate and host cell to facilitate motility...”
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  4. 14404
    Immunologically programming the tumor microenvironment induces the pattern recognition receptor NLRC4-dependent antitumor immunity
    “.... We also made a striking finding that NLRC4, not TLR5, is required for Flagrp170-mediated antitumor...”
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  5. 14405
    In silico trials predict that combination strategies for enhancing vesicular stomatitis oncolytic virus are determined by tumor aggressivity
    “...Background Immunotherapies, driven by immune-mediated antitumorigenicity, offer the potential...”
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  6. 14406
    Inhibition of the Super Elongation Complex Suppresses Herpes Simplex Virus Immediate Early Gene Expression, Lytic Infection, and Reactivation from Latency
    “.... Most importantly, this supports the model that signal-mediated induction of SEC-P-TEFb levels can...”
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  7. 14407
    Archaeal Chromatin Proteins Cren7 and Sul7d Compact DNA by Bending and Bridging
    “... to mediate DNA bridging, and this previously unknown property of the proteins allows DNA to be packaged...”
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  8. 14408
    Selection for Reducing Energy Cost of Protein Production Drives the GC Content and Amino Acid Composition Bias in Gene Transfer Agents
    “... of the energy cost of GTA particle production. We hypothesize that GTAs are dedicated devices mediating...”
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  9. 14409
    The <italic toggle="yes">Plasmodium falciparum</italic> Artemisinin Susceptibility-Associated AP-2 Adaptin μ Subunit is Clathrin Independent and Essential for Schizont Maturation
    “... development in blood but does not have any role in clathrin-mediated endocytosis. This suggests that a...”
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  10. 14410
    The Nitrite Transporter Facilitates Biofilm Formation via Suppression of Nitrite Reductase and Is a New Antibiofilm Target in <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
    por Ji-Su Park, Ha-Young Choi, Won-Gon Kim
    Publicado 2020
    “... for NO-mediated biofilm formation, which was previously not understood. IMPORTANCE Bacterial biofilms play roles...”
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  11. 14411
    Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance
    “... in N. gonorrhoeae is the multiple transferrable resistance (Mtr) pump, which mediates resistance to a...”
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  12. 14412
    An Essential Membrane Protein Modulates the Proteolysis of LpxC to Control Lipopolysaccharide Synthesis in <named-content content-type="genus-species">Escherichia coli</named-content>
    “... this balance is the committed step of LPS synthesis mediated by LpxC. Levels of this enzyme are controlled...”
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  13. 14413
    Roles of ATP Hydrolysis by FtsEX and Interaction with FtsA in Regulation of Septal Peptidoglycan Synthesis and Hydrolysis
    “... by FtsEX, but not ATP hydrolysis, is required to promote cell separation when the NlpD-mediated cell...”
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  14. 14414
    The Bacterial DNA Binding Protein MatP Involved in Linking the Nucleoid Terminal Domain to the Divisome at Midcell Interacts with Lipid Membranes
    “..., one of them being the linkage between the chromosomal Ter macrodomain and the Z-ring mediated by MatP...”
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  15. 14415
    Suppression of Drug Resistance Reveals a Genetic Mechanism of Metabolic Plasticity in Malaria Parasites
    “... parasites, we selected for suppression of HAD2-mediated FSM resistance and uncovered hypomorphic suppressor...”
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  16. 14416
    Cross Talk between Chemosensory Pathways That Modulate Chemotaxis and Biofilm Formation
    “... regulator CheY2 but also one of the response regulators from the pathway mediating biofilm formation, FlmD...”
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  17. 14417
    Examining a DNA Replication Requirement for Bacteriophage λ Red- and Rac Prophage RecET-Promoted Recombination in <named-content content-type="genus-species">Escherichia coli</named-content>
    “... DNA to create a three-stranded region. Here, in vivo experiments show that recombinase-mediated...”
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  18. 14418
    Lifestyle Evolution in Cyanobacterial Symbionts of Sponges
    “...” group was mostly related to immune system features, potential for siderophore-mediated iron transport...”
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  19. 14419
    Human Mesenchymal Stem Cells of Diverse Origins Support Persistent Infection with Kaposi’s Sarcoma-Associated Herpesvirus and Manifest Distinct Angiogenic, Invasive, and Transforming Phenotypes
    “... that mediated KSHV-induced angiogenic activity by activating the AKT pathway. These results indicated that human...”
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  20. 14420
    Biotic Interactions Shape the Ecological Distributions of <italic toggle="yes">Staphylococcus</italic> Species
    “...-negative staphylococcus (CNS) species, we demonstrate that fungi can mediate the ecological distributions...”
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