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  1. 15281
    Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo.
    “... is mediated by the overlapping action of pro-apoptotic BH3-only proteins, including but not solely involving...”
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  2. 15282
    Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.
    “...) production partly by blocking the TRIM25 ubiquitin E3 ligase-mediated Lys63-linked ubiquitination...”
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  3. 15283
    Global functional analyses of cellular responses to pore-forming toxins.
    “...-mediated PFT protection pathway, protects C. elegans against both small-pore and large-pore PFTs...”
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  4. 15284
    Target inhibition networks: predicting selective combinations of druggable targets to block cancer survival pathways.
    “... validated by means of systematic siRNA-mediated silencing of the selected targets and their pairwise...”
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  5. 15285
    The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein.
    “... mediated activation of an IFN-β reporter and secretion of IFN as determined by bioassay. Of note, the PB1-F...”
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  6. 15286
    Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis.
    “... into retroviral biology, human cancer genetics and the safety of vector-mediated gene therapy....”
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  7. 15287
    Functional specialization of the small interfering RNA pathway in response to virus infection.
    “... target inhibition remains unclear. Here, we characterize the response mechanism mediated by siRNAs...”
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  8. 15288
    Inducible deletion of CD28 prior to secondary nippostrongylus brasiliensis infection impairs worm expulsion and recall of protective memory CD4⁺ T cell responses.
    “... with the gastrointestinal nematode Nippostronglus brasiliensis. Disruption of CD28 mediated costimulation impairs...”
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  9. 15289
    Hepatitis B virus infection and immunopathogenesis in a humanized mouse model: induction of human-specific liver fibrosis and M2-like macrophages.
    “... in humanized mice. In addition, we found that the HBV mediated liver disease was associated with high level...”
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  10. 15290
    HTLV-1 bZIP factor induces inflammation through labile Foxp3 expression.
    “...3⁻T cells producing IFN-γ. The HBZ-mediated proinflammatory phenotype of CD4⁺ T cells is implicated...”
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  11. 15291
    Molecular cloning and characterization of novel glutamate-gated chloride channel subunits from Schistosoma mansoni.
    “...Cys-loop ligand-gated ion channels (LGICs) mediate fast ionotropic neurotransmission...”
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  12. 15292
    Kaposi's sarcoma associated herpesvirus tegument protein ORF75 is essential for viral lytic replication and plays a critical role in the antagonization of ND10-instituted intrinsic immunity.
    “... of ORF75, we could further corroborate the role of ORF75 in the antagonization of ND10-mediated intrinsic...”
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  13. 15293
    Allelic variation on murine chromosome 11 modifies host inflammatory responses and resistance to Bacillus anthracis.
    “... in congenic mice is inherited in a recessive manner while the Nlrp1b-mediated response to LT is dominant...”
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  14. 15294
    IgG subclass and heavy chain domains contribute to binding and protection by mAbs to the poly γ-D-glutamic acid capsular antigen of Bacillus anthracis.
    “...Bacterial capsules are common targets for antibody-mediated immunity. The capsule of Bacillus...”
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  15. 15295
    The exopolysaccharide matrix modulates the interaction between 3D architecture and virulence of a mixed-species oral biofilm.
    “... were largely mediated by the S. mutans gtfB/gtfC genes, expression of which was enhanced...”
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  16. 15296
    Ablation of the regulatory IE1 protein of murine cytomegalovirus alters in vivo pro-inflammatory TNF-alpha production during acute infection.
    “.... The ie1- mediated inhibition of TNFα production has a similar quantitative phenotype profile in infection...”
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  17. 15297
    Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLCγ1 and activating NFAT1-dependent RCAN1 expression.
    “... of the KSHV K15 protein in KSHV-mediated angiogenesis, we carried out a genome wide gene expression analysis...”
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  18. 15298
    Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1β is deleterious.
    “... and IL-18 and are critical for inflammasome-mediated resistance to melioidosis. In vitro production of IL...”
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  19. 15299
    A candidate HIV/AIDS vaccine (MVA-B) lacking vaccinia virus gene C6L enhances memory HIV-1-specific T-cell responses.
    “...+ and CD8+ T-cell memory immune responses, with most of the HIV-1 responses mediated by the CD8+ T-cell...”
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  20. 15300
    PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1.
    “... and bimolecular fluorescence complementation assays. The binding was also confirmed to be mediated...”
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